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• 31. [Article] Comprehensive examination of the differences in thermoregulatory and ventilatory responses between humans with and without a PFO under different environmental conditions

  The existence of a patent foramen ovale (PFO) has been known about for nearly 2,000 years. The prevalence of a PFO has been shown to be 25-40% in the general population. Despite the fact that blood flowing ...

  Citation × Citation Citation Abstract Copy Title: Comprehensive examination of the differences in thermoregulatory and ventilatory responses between humans with and without a PFO under different environmental conditions Author: Davis, James Year: 2016 The existence of a patent foramen ovale (PFO) has been known about for nearly 2,000 years. The prevalence of a PFO has been shown to be 25-40% in the general population. Despite the fact that blood flowing through a PFO acts as a shunt, there has been little research looking at the effect a PFO has on physiology in otherwise healthy humans. In Chapter IV, the effect of a PFO on core temperature (Tcore) prior to, and during exercise, was investigated. The design of this experiment included appropriate controls for a thermoregulatory study (i.e. measuring at same time of day, appropriate hydration and food intake, etc.). Results from this study indicate that subjects with a PFO (PFO+) have a Tcore that is ~0.4°C higher at rest and during exercise than subjects without a PFO (PFO–). Additionally, this study showed that PFO– subjects do not increase Tcore to the same extent breathing cold air as they do breathing ambient air during a 10-minute exercise bout, whereas there was no difference in Tcore increase between these two conditions for PFO+ subjects. These findings suggest that the difference in Tcore between PFO+ and PFO– subjects is potentially due to differences in respiratory heat loss. The studies for Chapter V examined differences in thermoregulatory and ventilatory responses during hot water (40°C) and cold water (20°C) immersion. This study found that compared to PFO– subjects, PFO+ subjects 1) increase Tcore at the same rate during hot water immersion and 2) do not cool off as quickly during cold water immersion. Additionally, in subjects who reached a ventilatory threshold, PFO+ subjects had blunted ventilatory responses to increased Tcore compared to PFO– subjects. Finally, in Chapter VI it was shown that PFO+ subjects have blunted ventilatory responses during acute exposure to hyperoxic and normoxic hypercapnia. However, there were no differences in ventilatory responses between PFO+ and PFO– subjects during exposure to either isocapnic or poikilocapnic hypoxia. These findings suggest that PFO+ subjects have a blunted central chemoreflex. This dissertation contains previously, unpublished co-authored material. Title: Comprehensive examination of the differences in thermoregulatory and ventilatory responses between humans with and without a PFO under different environmental conditions Author: Davis, James Year: 2016 The existence of a patent foramen ovale (PFO) has been known about for nearly 2,000 years. The prevalence of a PFO has been shown to be 25-40% in the general population. Despite the fact that blood flowing through a PFO acts as a shunt, there has been little research looking at the effect a PFO has on physiology in otherwise healthy humans. In Chapter IV, the effect of a PFO on core temperature (Tcore) prior to, and during exercise, was investigated. The design of this experiment included appropriate controls for a thermoregulatory study (i.e. measuring at same time of day, appropriate hydration and food intake, etc.). Results from this study indicate that subjects with a PFO (PFO+) have a Tcore that is ~0.4°C higher at rest and during exercise than subjects without a PFO (PFO–). Additionally, this study showed that PFO– subjects do not increase Tcore to the same extent breathing cold air as they do breathing ambient air during a 10-minute exercise bout, whereas there was no difference in Tcore increase between these two conditions for PFO+ subjects. These findings suggest that the difference in Tcore between PFO+ and PFO– subjects is potentially due to differences in respiratory heat loss. The studies for Chapter V examined differences in thermoregulatory and ventilatory responses during hot water (40°C) and cold water (20°C) immersion. This study found that compared to PFO– subjects, PFO+ subjects 1) increase Tcore at the same rate during hot water immersion and 2) do not cool off as quickly during cold water immersion. Additionally, in subjects who reached a ventilatory threshold, PFO+ subjects had blunted ventilatory responses to increased Tcore compared to PFO– subjects. Finally, in Chapter VI it was shown that PFO+ subjects have blunted ventilatory responses during acute exposure to hyperoxic and normoxic hypercapnia. However, there were no differences in ventilatory responses between PFO+ and PFO– subjects during exposure to either isocapnic or poikilocapnic hypoxia. These findings suggest that PFO+ subjects have a blunted central chemoreflex. This dissertation contains previously, unpublished co-authored material. Close

• 32. [Article] THE EFFECT OF A PATENT FORAMEN OVALE ON THERMOREGULATORY AND VENTILATORY RESPONSES DURING PASSIVE HEATING AND COOLING

  41 pages. A thesis presented to the Department of Human Physiology and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Science, ...

  Citation × Citation Citation Abstract Copy Title: THE EFFECT OF A PATENT FORAMEN OVALE ON THERMOREGULATORY AND VENTILATORY RESPONSES DURING PASSIVE HEATING AND COOLING Author: Hay, Madeline Year: 2016 41 pages. A thesis presented to the Department of Human Physiology and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Science, Spring 2016. Title: THE EFFECT OF A PATENT FORAMEN OVALE ON THERMOREGULATORY AND VENTILATORY RESPONSES DURING PASSIVE HEATING AND COOLING Author: Hay, Madeline Year: 2016 41 pages. A thesis presented to the Department of Human Physiology and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Science, Spring 2016. Close

• 33. [Article] Galena Watershed analysis--Supplement 2002

  818 pp. Tables, figures, maps, references, glossary, appendices, illus. "Analysis was performed on 49,4733 acres of the Davis, Placer, Vinegar, Tincup, Little Butte, Butte, Vincent, Little Boulder, Deerhorn ...

  Citation × Citation Citation Abstract Copy Title: Galena Watershed analysis--Supplement 2002 Author: Blue Mountain Ranger District (Or.) Year: 2008, 2003 818 pp. Tables, figures, maps, references, glossary, appendices, illus. "Analysis was performed on 49,4733 acres of the Davis, Placer, Vinegar, Tincup, Little Butte, Butte, Vincent, Little Boulder, Deerhorn and Granite Boulder subwatersheds and the tributaries to the Middle- Fork of the John Day River (Chapters 1-4 this document, see also Map A page 1 and Appendix E, Maps 1-31). The Middle Fork of the John Day River originates south of the North Fork of the John Day River in the Blue Mountains, and flows westerly for approximately 75 miles, then merges with the North Fork about 18 miles above Monument, Oregon. The analysis area is located about 25 air miles northeast of John Day, Oregon." Captured June 11, 2008. Title: Galena Watershed analysis--Supplement 2002 Author: Blue Mountain Ranger District (Or.) Year: 2008, 2003 818 pp. Tables, figures, maps, references, glossary, appendices, illus. "Analysis was performed on 49,4733 acres of the Davis, Placer, Vinegar, Tincup, Little Butte, Butte, Vincent, Little Boulder, Deerhorn and Granite Boulder subwatersheds and the tributaries to the Middle- Fork of the John Day River (Chapters 1-4 this document, see also Map A page 1 and Appendix E, Maps 1-31). The Middle Fork of the John Day River originates south of the North Fork of the John Day River in the Blue Mountains, and flows westerly for approximately 75 miles, then merges with the North Fork about 18 miles above Monument, Oregon. The analysis area is located about 25 air miles northeast of John Day, Oregon." Captured June 11, 2008. Close

• 34. [Article] Swiftwater 2004 instream restoration projects decision record

  3 pp. North Fork Big Tom Folley Creek (T21S, R7W, Sections 35 and 26), Big Tom Folley Creek (T22 and 21S, R7W, Sections 2 and 36), and Susan Creek (T26S, R2W, Section 14; W.M.) Captured July 24, 2008.

  Citation × Citation Citation Abstract Copy Title: Swiftwater 2004 instream restoration projects decision record Author: United States. Bureau of Land Management. Roseburg District Office Year: 2008, 2004 3 pp. North Fork Big Tom Folley Creek (T21S, R7W, Sections 35 and 26), Big Tom Folley Creek (T22 and 21S, R7W, Sections 2 and 36), and Susan Creek (T26S, R2W, Section 14; W.M.) Captured July 24, 2008. Title: Swiftwater 2004 instream restoration projects decision record Author: United States. Bureau of Land Management. Roseburg District Office Year: 2008, 2004 3 pp. North Fork Big Tom Folley Creek (T21S, R7W, Sections 35 and 26), Big Tom Folley Creek (T22 and 21S, R7W, Sections 2 and 36), and Susan Creek (T26S, R2W, Section 14; W.M.) Captured July 24, 2008. Close

• 35. [Article] Deep Creek watershed restoration environmental assessment

  128 pp. Tables, map, index, glossary, references, appendices. T. 13 S., R. 22 E., Sections 11, 13, 14, 23-26, 35, 36 T. 13 S., R. 23 E., Sections 7-36 T. 13 S., R. 24 E., Sections 18, 19, 29-32 T. 14 S., ...

  Citation × Citation Citation Abstract Copy Title: Deep Creek watershed restoration environmental assessment Author: Paulina Ranger District (Or.) Year: 2008, 2004 128 pp. Tables, map, index, glossary, references, appendices. T. 13 S., R. 22 E., Sections 11, 13, 14, 23-26, 35, 36 T. 13 S., R. 23 E., Sections 7-36 T. 13 S., R. 24 E., Sections 18, 19, 29-32 T. 14 S., R. 22 E., Sections 1, 2, 11-14, 23-27, 35, 36 T. 14 S., R. 23 E., Sections 1-36 T. 14 S., R. 24 E., Sections 5-8, 16-18, 19-21, 28-32 T. 15 S., R. 22 E., Sections 1, 2 T. 15 S., R. 23 E., Sections 5, 6. Captured May 30, 2007. Title: Deep Creek watershed restoration environmental assessment Author: Paulina Ranger District (Or.) Year: 2008, 2004 128 pp. Tables, map, index, glossary, references, appendices. T. 13 S., R. 22 E., Sections 11, 13, 14, 23-26, 35, 36 T. 13 S., R. 23 E., Sections 7-36 T. 13 S., R. 24 E., Sections 18, 19, 29-32 T. 14 S., R. 22 E., Sections 1, 2, 11-14, 23-27, 35, 36 T. 14 S., R. 23 E., Sections 1-36 T. 14 S., R. 24 E., Sections 5-8, 16-18, 19-21, 28-32 T. 15 S., R. 22 E., Sections 1, 2 T. 15 S., R. 23 E., Sections 5, 6. Captured May 30, 2007. Close

• 36. [Article] Swiftwater 2004 instream restoration projects environmental assessment

  17 pp. Tables, maps, appendices, references. North Fork Big Tom Folley: Township 21 South, Range 7 West, Sections 35 and 26; Big Tom Folley Creek: Township 22 and 21 South, Range 7 West, Sections 2 and ...

  Citation × Citation Citation Abstract Copy Title: Swiftwater 2004 instream restoration projects environmental assessment Author: United States. Bureau of Land Management. Roseburg District Office Year: 2008, 1995 17 pp. Tables, maps, appendices, references. North Fork Big Tom Folley: Township 21 South, Range 7 West, Sections 35 and 26; Big Tom Folley Creek: Township 22 and 21 South, Range 7 West, Sections 2 and 36; Susan Creek: Township 26 South, Range 2 West, Section 14. Captured July 27, 2007. Title: Swiftwater 2004 instream restoration projects environmental assessment Author: United States. Bureau of Land Management. Roseburg District Office Year: 2008, 1995 17 pp. Tables, maps, appendices, references. North Fork Big Tom Folley: Township 21 South, Range 7 West, Sections 35 and 26; Big Tom Folley Creek: Township 22 and 21 South, Range 7 West, Sections 2 and 36; Susan Creek: Township 26 South, Range 2 West, Section 14. Captured July 27, 2007. Close

• 37. [Article] Recent Mafic Eruptions at Newberry Volcano and in the Central Oregon Cascades: Physical Volcanology and Implications for Hazards

  Mafic eruptions have been the dominant form of volcanic activity in central Oregon throughout the Holocene. These eruptions have produced cinder cones, extensive lava flows, and tephra blankets. In most ...

  Citation × Citation Citation Abstract Copy Title: Recent Mafic Eruptions at Newberry Volcano and in the Central Oregon Cascades: Physical Volcanology and Implications for Hazards Author: McKay, Daniele Year: 2012 Mafic eruptions have been the dominant form of volcanic activity in central Oregon throughout the Holocene. These eruptions have produced cinder cones, extensive lava flows, and tephra blankets. In most cases, the extent and volume of the tephra blankets has not been determined, despite the fact that future tephra production would pose considerable hazards to transportation, infrastructure, and public health. The economy of the region, which is largely based in tourism, would also be negatively impacted. For this reason, developing a better understanding of the extent and dynamics of tephra production at recent mafic vents is critical, both in terms of mitigating the hazards associated with future eruptions and in improving our scientific understanding of explosive mafic activity. Here I present detailed field and laboratory studies of tephra from recent mafic vents at Newberry Volcano and in the central Oregon High Cascades. Studies of Newberry vents show that eruption style is strongly correlated with eruptive volume, that extensive magma storage and assimilation occurred prior to the eruption of these vents, and that minimum pre-magmatic water content as recorded by plagioclase was 2.5 wt.%. Detailed mapping and physical studies of tephra deposits from High Cascades vents show that several recent eruptions produced extensive tephra deposits. These deposits are physically similar to well-documented historic eruptions that have been characterized as violent strombolian. At least one Cascade cinder cone (Sand Mountain) produced a tephra deposit that is unusually large in volume and characterized by uniformly fine-grained clasts, which is interpreted as evidence for syn-eruptive interaction with external water. Microtextural characteristics of tephra, along with an evaluation of possible water sources, support this interpretation. These investigations demonstrate that magma storage and eruption style at mafic vents is both variable and complex. Additionally, these studies show that cinder cones in central Oregon have the potential to erupt much more explosively than previously assumed. The results of this study will be an important tool for developing comprehensive regional hazard assessments. This dissertation includes previously published and unpublished co-authored material. Title: Recent Mafic Eruptions at Newberry Volcano and in the Central Oregon Cascades: Physical Volcanology and Implications for Hazards Author: McKay, Daniele Year: 2012 Mafic eruptions have been the dominant form of volcanic activity in central Oregon throughout the Holocene. These eruptions have produced cinder cones, extensive lava flows, and tephra blankets. In most cases, the extent and volume of the tephra blankets has not been determined, despite the fact that future tephra production would pose considerable hazards to transportation, infrastructure, and public health. The economy of the region, which is largely based in tourism, would also be negatively impacted. For this reason, developing a better understanding of the extent and dynamics of tephra production at recent mafic vents is critical, both in terms of mitigating the hazards associated with future eruptions and in improving our scientific understanding of explosive mafic activity. Here I present detailed field and laboratory studies of tephra from recent mafic vents at Newberry Volcano and in the central Oregon High Cascades. Studies of Newberry vents show that eruption style is strongly correlated with eruptive volume, that extensive magma storage and assimilation occurred prior to the eruption of these vents, and that minimum pre-magmatic water content as recorded by plagioclase was 2.5 wt.%. Detailed mapping and physical studies of tephra deposits from High Cascades vents show that several recent eruptions produced extensive tephra deposits. These deposits are physically similar to well-documented historic eruptions that have been characterized as violent strombolian. At least one Cascade cinder cone (Sand Mountain) produced a tephra deposit that is unusually large in volume and characterized by uniformly fine-grained clasts, which is interpreted as evidence for syn-eruptive interaction with external water. Microtextural characteristics of tephra, along with an evaluation of possible water sources, support this interpretation. These investigations demonstrate that magma storage and eruption style at mafic vents is both variable and complex. Additionally, these studies show that cinder cones in central Oregon have the potential to erupt much more explosively than previously assumed. The results of this study will be an important tool for developing comprehensive regional hazard assessments. This dissertation includes previously published and unpublished co-authored material. Close

• 38. [Article] Chronic passive heat therapy as a novel means of improving vascular function in sedentary humans

  Cardiovascular disease is the leading cause of death in the developed world. The majority of cardiovascular diseases are characterized by disorders of the arteries, predominantly caused by endothelial ...

  Citation × Citation Citation Abstract Copy Title: Chronic passive heat therapy as a novel means of improving vascular function in sedentary humans Author: Brunt, Vienna Year: 2016 Cardiovascular disease is the leading cause of death in the developed world. The majority of cardiovascular diseases are characterized by disorders of the arteries, predominantly caused by endothelial dysfunction and arterial stiffening. Passive heat stress results in elevations in core temperature (inducing heat shock protein expression) and changes in cardiovascular hemodynamics, such as increased cardiac output and shear stress, that are similar to exercise. Thus, repeated passive heat stress (“heat therapy”) may provide an alternative means of improving cardiovascular health, particularly for patients with limited exercise tolerance and/or capabilities. Therefore, the goal of this dissertation was to perform integrative studies to determine the effects of heat therapy on vascular function and the associated cellular pathways in young, sedentary humans. Twenty subjects were assigned to participate in 8 weeks (4-5x/week) of heat therapy (N=10; immersion in a 40.5°C bath sufficient to maintain rectal temperature ≥38.5°C for 60 min/session) or thermoneutral water immersion (N=10; sham). As discussed in Chapter V, we found that heat therapy improved numerous well-established biomarkers of conduit vessel/macrovascular function, including flow-mediated dilation (a measure of endothelial function), arterial stiffness, intima media thickness, and blood pressure. Heat therapy also improved microvascular function, as discussed in Chapter VI, measured as improved cutaneous thermal hyperemia and nitric oxide-dependent dilation (the difference between microdialysis sites receiving Lactated Ringer’s [control] and nitric oxide synthase inhibition). No changes were observed in any variables in sham subjects. In Chapter VII, we showed that both direct cellular heating and serum collected from human subjects following heat therapy improved nitric oxide bioavailability and angiogenesis in cultured endothelial cells, providing potential mechanisms by which heat therapy improves vascular function in vivo. Therefore, the studies described herein provide comprehensive evidence that passive heat therapy improves vascular health and insight into the mechanisms involved. Our data presented in Chapters IV-VII, combined with pilot data we conducted in spinal cord injured individuals (Chapter VIII), strongly indicate that passive heat therapy could be used as a simple and effective tool to improve cardiovascular health in a variety of patient populations. This dissertation includes published and unpublished co-authored material. Title: Chronic passive heat therapy as a novel means of improving vascular function in sedentary humans Author: Brunt, Vienna Year: 2016 Cardiovascular disease is the leading cause of death in the developed world. The majority of cardiovascular diseases are characterized by disorders of the arteries, predominantly caused by endothelial dysfunction and arterial stiffening. Passive heat stress results in elevations in core temperature (inducing heat shock protein expression) and changes in cardiovascular hemodynamics, such as increased cardiac output and shear stress, that are similar to exercise. Thus, repeated passive heat stress (“heat therapy”) may provide an alternative means of improving cardiovascular health, particularly for patients with limited exercise tolerance and/or capabilities. Therefore, the goal of this dissertation was to perform integrative studies to determine the effects of heat therapy on vascular function and the associated cellular pathways in young, sedentary humans. Twenty subjects were assigned to participate in 8 weeks (4-5x/week) of heat therapy (N=10; immersion in a 40.5°C bath sufficient to maintain rectal temperature ≥38.5°C for 60 min/session) or thermoneutral water immersion (N=10; sham). As discussed in Chapter V, we found that heat therapy improved numerous well-established biomarkers of conduit vessel/macrovascular function, including flow-mediated dilation (a measure of endothelial function), arterial stiffness, intima media thickness, and blood pressure. Heat therapy also improved microvascular function, as discussed in Chapter VI, measured as improved cutaneous thermal hyperemia and nitric oxide-dependent dilation (the difference between microdialysis sites receiving Lactated Ringer’s [control] and nitric oxide synthase inhibition). No changes were observed in any variables in sham subjects. In Chapter VII, we showed that both direct cellular heating and serum collected from human subjects following heat therapy improved nitric oxide bioavailability and angiogenesis in cultured endothelial cells, providing potential mechanisms by which heat therapy improves vascular function in vivo. Therefore, the studies described herein provide comprehensive evidence that passive heat therapy improves vascular health and insight into the mechanisms involved. Our data presented in Chapters IV-VII, combined with pilot data we conducted in spinal cord injured individuals (Chapter VIII), strongly indicate that passive heat therapy could be used as a simple and effective tool to improve cardiovascular health in a variety of patient populations. This dissertation includes published and unpublished co-authored material. Close

• 39. [Article] NITRIC OXIDE SIGNALLING PATHWAYS FOLLOWING CHRONIC PASSIVE HEAT THERAPY

  64 pages. A thesis presented to the Department of Human Physiology and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Science, ...

  Citation × Citation Citation Abstract Copy Title: NITRIC OXIDE SIGNALLING PATHWAYS FOLLOWING CHRONIC PASSIVE HEAT THERAPY Author: Eymann, Taylor Year: 2016 64 pages. A thesis presented to the Department of Human Physiology and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Science, Spring 2016. Title: NITRIC OXIDE SIGNALLING PATHWAYS FOLLOWING CHRONIC PASSIVE HEAT THERAPY Author: Eymann, Taylor Year: 2016 64 pages. A thesis presented to the Department of Human Physiology and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Science, Spring 2016. Close

• 40. [Article] Remote measurement of gravel-bed river depths and analysis of the geomorphic response of rivers to canals and small dams

  xviii, 128 p. : ill. (some col.)

  Citation × Citation Citation Abstract Copy Title: Remote measurement of gravel-bed river depths and analysis of the geomorphic response of rivers to canals and small dams Author: Walther, Suzanne Corinna Year: 2011, 2010 xviii, 128 p. : ill. (some col.) Title: Remote measurement of gravel-bed river depths and analysis of the geomorphic response of rivers to canals and small dams Author: Walther, Suzanne Corinna Year: 2011, 2010 xviii, 128 p. : ill. (some col.) Close