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Regulations
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Author
Brass, Felicitas
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Author
Hardtke-Wolenski, Matthias
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Author
Malek, Nisar P.
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Schirmacher, Peter
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Author
Singer, Jeffrey D.
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Subject
Liver cells -- Cancer
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Medical Cell Biology
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Subject
Stem cells -- DNA damage
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Database
PDX Scholar
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1. [Article] The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells
Cyclin E is often overexpressed in cancer tissue, leading to genetic instability and aneuploidy. Cullin 3 (Cul3) is a component of the BTB-Cul3-Rbx1 (BCR) ubiquitin ligase that is involved in the turnover ...Citation